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CBD CASE STUDIES

Research Shows CBD Benefits 50+ Conditions

by Aaron Cadena April 17, 2019

Over the last few years, Cannabidiol (CBD) has exploded into the world of health and wellness.

With dozens of natural benefits, CBD has been used to ease conditionssuch as anxiety, epilepsy, neurodegenerative diseases and more.

For the last century, researchers have assessed CBD as a treatment for numerous conditions. More than 50, in fact.

What these studies show is profound.

If you are looking for research on CBD benefits for a certain condition, you will find it here.

From mental health to MS, we have gathered a collection of more than 250 resources, organized by condition.

Browse Medical Research Based on Condition

#CONDITIONMEDICAL RESEARCH
5CBD FOR ACNECannabidiol as a Treatment for Acne?
CBD FOR ACNECannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes
CBD FOR ACNEThe endocannabinoid system of the skin in health and disease: Novel perspectives and therapeutic opportunities
CBD FOR ACNEEndocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling
CBD FOR ACNEEndocannabinoid signaling and epidermal differentiation
6CBD FOR ADD / ADHDSearching for a Neurobiological Basis for Self-Medication Theory in ADHD Comorbid With Substance Use Disorders
CBD FOR ADD / ADHDCannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague-Dawley rats
CBD FOR ADD / ADHDSubtypes of Attention Deficit — Hyperactivity Disorder (ADHD) and cannabis use
CBD FOR ADD / ADHDChildhood and current ADHD symptom dimensions are associated with more severe cannabis outcomes in college students
CBD FOR ADD / ADHDOral delta 9-tetrahydrocannabinol improved refractory Gilles de la Tourette syndrome in an adolescent by increasing intracortical inhibition: A case report
CBD FOR ADD / ADHDFitness to drive in spite (because) of THC
10CBD FOR ADDICTIONCannabidiol reduces cigarette consumption in tobacco smokers
CBD FOR ADDICTIONCannabidiol inhibits the reward-facilitating effect of morphine
CBD FOR ADDICTIONCannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
CBD FOR ADDICTIONDifferential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats
CBD FOR ADDICTIONImpact of Cannabis Use during Stabilization on Methadone Maintenance Treatment
CBD FOR ADDICTIONMedical cannabis laws and opioid analgesic overdose mortality in the United States, 1999-2010
CBD FOR ADDICTIONDysregulation of cannabinoid CB1 receptor and associated signaling networks in brains of cocaine addicts and cocaine-treated rodents
CBD FOR ADDICTIONComparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity
CBD FOR ADDICTIONTransdermal delivery of cannabidiol attenuates binge alcohol-induced neurodegeneration in a rodent model of an alcohol use disorder
CBD FOR ADDICTIONCannabidiol for the treatment of cannabis withdrawal syndrome
4CBD FOR ALSCannabis and amyotrophic lateral sclerosis: hypothetical and practical applications, and a call for clinical trials
CBD FOR ALSALS: delayed disease progression in mice by treatment with a cannabinoid
CBD FOR ALSThe (Endo)Cannabinoid System in Multiple Sclerosis and ALS
CBD FOR ALSSurvey of cannabis use in patients with ALS
16CBD FOR ALZHEIMERSThe therapeutic potential of the endocannabinoid system for Alzheimer’s disease
CBD FOR ALZHEIMERSEndocannabinoid signalling in Alzheimer’s disease
CBD FOR ALZHEIMERSA molecular link between the active component of marijuana and Alzheimer’s disease pathology
CBD FOR ALZHEIMERSNeuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells
CBD FOR ALZHEIMERSThe Potential Therapeutic Effects of THC on Alzheimer’s Disease
CBD FOR ALZHEIMERSThe Role of Endocannabinoid Signaling in the Molecular Mechanisms of Neurodegeneration in Alzheimer’s Disease
CBD FOR ALZHEIMERSCannabinoids for the treatment of dementia
CBD FOR ALZHEIMERSCannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression
CBD FOR ALZHEIMERSCannabidiol: A promising drug for neurodegenerative disorders?
CBD FOR ALZHEIMERSCannabinoid receptor 1 deficiency in a mouse model of Alzheimer’s disease leads to enhanced cognitive impairment despite of a reduction in amyloid deposition
CBD FOR ALZHEIMERSThe role of the endocannabinoid system in Alzheimer’s disease: facts and hypotheses
CBD FOR ALZHEIMERSThe role of phytochemicals in the treatment and prevention of dementia
CBD FOR ALZHEIMERSCannabinoids for the treatment of dementia
CBD FOR ALZHEIMERSCannabidiol Promotes Amyloid Precursor Protein Ubiquitination and Reduction of Beta Amyloid Expression in SHSY5YAPP+ Cells Through PPARγ Involvement
CBD FOR ALZHEIMERSCannabinoids for treatment of Alzheimer’s disease: moving toward the clinic
CBD FOR ALZHEIMERSCan Marijuana Prevent Alzheimer’s?
4CBD FOR ANOREXIALeptin, ghrelin, and endocannabinoids: Potential therapeutic targets in anorexia nervosa
CBD FOR ANOREXIAThe role of the endocannabinoid system in eating disorders: Neurochemical and behavioural preclinical evidence
CBD FOR ANOREXIACancer cachexia and cannabinoids
CBD FOR ANOREXIABrain Type 1 Cannabinoid Receptor Availability in Patients with Anorexia and Bulimia Nervosa
9CBD FOR ANXIETYCannabidiol, a Cannabis sativa constituent, as an anxiolytic drug
CBD FOR ANXIETYAntidepressant-Like and Anxiolytic-Like Effects of Cannabidiol: A Chemical Compound of Cannabis Sativa
CBD FOR ANXIETYCannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients
CBD FOR ANXIETYNeural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder
CBD FOR ANXIETYCentral anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation
CBD FOR ANXIETYEffects of cannabidiol (CBD) on regional cerebral blood flow
CBD FOR ANXIETYThe anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors
CBD FOR ANXIETYThe anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
CBD FOR ANXIETYPlant-based medicines for anxiety disorders, part 2: A review of clinical studies with supporting preclinical evidence
4CBD FOR ATHEROSCLEROSISThe role of the endocannabinoid system in atherosclerosis
CBD FOR ATHEROSCLEROSISCannabinoid receptors in atherosclerosis
CBD FOR ATHEROSCLEROSISThe potential use of cannabidiol in the therapy of metabolic syndrome
CBD FOR ATHEROSCLEROSISLow dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
4CBD FOR ARTHRITISPreliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
CBD FOR ARTHRITISThe nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
CBD FOR ARTHRITISThe abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55
CBD FOR ARTHRITISArthritis and cannabinoids
5CBD FOR ASTHMAThe role of cannabinoids in inflammatory modulation of allergic respiratory disorders, inflammatory pain and ischemic stroke
CBD FOR ASTHMAAllergen challenge increases anandamide in bronchoalveolar fluid of patients with allergic asthma
CBD FOR ASTHMAActivation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs
CBD FOR ASTHMAEndogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways
CBD FOR ASTHMABronchodilator effect of delta1-tetrahydrocannabinol
5CBD FOR AUTISMMutations found in individuals with autism interfere with endocannabinoid signaling in the brain
CBD FOR AUTISMCannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders
CBD FOR AUTISMA novel approach to the symptomatic treatment of autism
CBD FOR AUTISMConsequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders
CBD FOR AUTISMTargeting the endocannabinoid system in the treatment of fragile X syndrome
5CBD FOR BIPOLAR AFFECTIVE DISORDERCannabinoids in bipolar affective disorder: A review and discussion of their therapeutic potential
CBD FOR BIPOLAR AFFECTIVE DISORDERCannabidiol was ineffective for manic episode of bipolar affective disorder
CBD FOR BIPOLAR AFFECTIVE DISORDEREffects of Co-occurring Cannabis Use Disorders on the Course of Bipolar Disorder After a First Hospitalization for Mania
CBD FOR BIPOLAR AFFECTIVE DISORDERDoes Cannabis Use Affect Treatment Outcome in Bipolar Disorder?: A Longitudinal Analysis
CBD FOR BIPOLAR AFFECTIVE DISORDERThe Use of Cannabis as a Mood Stabilizer in Bipolar Disorder: Anecdotal Evidence and the Need for Clinical Research
5CBD FOR CANCER – GENERALCannabidiol as potential anticancer drug
CBD FOR CANCER – GENERALCannabidiol inhibits angiogenesis by multiple mechanisms
CBD FOR CANCER – GENERALThe inhibitory effects of cannabidiol on systemic malignant tumors
CBD FOR CANCER – GENERALCannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1
CBD FOR CANCER – GENERALMarijuana fights cancer and helps manage side effects
4CBD FOR CANCER – LUNGCannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1C
CBD FOR CANCER – LUNGCOX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells
CBD FOR CANCER – LUNGDecrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells
CBD FOR CANCER – LUNGMedia ignored expert’s shocking findings that marijuana helps prevent lung cancer
5CBD FOR CANCER – PROSTATE/COLONTowards the use of non-psychoactive cannabinoids for prostate cancer
CBD FOR CANCER – PROSTATE/COLONIn Vitro Anticancer Activity of Plant-Derived Cannabidiol on Prostate Cancer Cell Lines
CBD FOR CANCER – PROSTATE/COLONInduction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent
CBD FOR CANCER – PROSTATE/COLONChemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
CBD FOR CANCER – PROSTATE/COLONInhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol
5CBD FOR CANCER – BREASTAntitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
CBD FOR CANCER – BREASTCannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy
CBD FOR CANCER – BREASTPathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis
CBD FOR CANCER – BREASTCannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
CBD FOR CANCER – BREASTCannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration
8CBD FOR CANCER – BRAINCannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival
CBD FOR CANCER – BRAINAntitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines(PubMed)
CBD FOR CANCER – BRAINSystematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas
CBD FOR CANCER – BRAINCannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism
CBD FOR CANCER – BRAINId-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target
CBD FOR CANCER – BRAINTriggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
CBD FOR CANCER – BRAINCannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect
CBD FOR CANCER – BRAINLocal delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme
4CBD FOR CANCER – LEUKEMIACannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression
CBD FOR CANCER – LEUKEMIACannabidiol-Induced Apoptosis in Human Leukemia Cells
CBD FOR CANCER – LEUKEMIACannabidiol Reduces Leukemic Cell Size – But Is It Important?
CBD FOR CANCER – LEUKEMIATargeting cannabinoid receptors to treat leukemia
4CBD FOR CANCER – SKINAnticancer activity of anandamide in human cutaneous melanoma cells
CBD FOR CANCER – SKINCannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpes virus-infected endothelium (PubMed)
CBD FOR CANCER – SKINCannabinoid receptors as novel targets for the treatment of melanoma
CBD FOR CANCER – SKINThe Cannabinoid Receptors Are Required for Ultraviolet-Induced Inflammation and Skin Cancer Development
4CBD FOR CANCER – ENDOCRINEEndocannabinoids in endocrine and related tumours
CBD FOR CANCER – ENDOCRINEA comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells
CBD FOR CANCER – ENDOCRINECannabinoids in pancreatic cancer: Correlation with survival and pain
CBD FOR CANCER – ENDOCRINECannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma
4CBD FOR CANCER – BLADDERTRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer
CBD FOR CANCER – BLADDERAssociation Between Cannabis Use and the Risk of Bladder Cancer
CBD FOR CANCER – BLADDERInhibitory Effect of Standardized Cannabis sativaExtract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility
CBD FOR CANCER – BLADDERBladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism
4CBD FOR CANCER – PAIN RELIEFMulticenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain
CBD FOR CANCER – PAIN RELIEFNabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial
CBD FOR CANCER – PAIN RELIEFMarijuana extract helps prevent chemo pain
CBD FOR CANCER – PAIN RELIEFAn Open-Label Extension Study to Investigate the Long-Term Safety and Tolerability of THC/CBD Oromucosal Spray and Oromucosal THC Spray in Patients With Terminal Cancer-Related Pain Refractory to Strong Opioid Analgesics
10CBD FOR CROHNS & COLITISCannabidiol in inflammatory bowel diseases: a brief overview
CBD FOR CROHNS & COLITISCannabis finds its way into treatment of Crohn’s disease
CBD FOR CROHNS & COLITISCannabidiol reduces intestinal inflammation through the control of neuroimmune axis
CBD FOR CROHNS & COLITISCannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis
CBD FOR CROHNS & COLITISThe effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis
CBD FOR CROHNS & COLITISTopical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice
CBD FOR CROHNS & COLITISCannabinoids and the gut: New developments and emerging concepts
CBD FOR CROHNS & COLITISEndocannabinoids and the gastrointestinal tract
CBD FOR CROHNS & COLITISCannabinoids and gastrointestinal motility: Animal and human studies
CBD FOR CROHNS & COLITISHergenrather presents study of Crohn’s patients as a template for clinical research on Cannabis
11CBD FOR DEPRESSIONEndocannabinoid system dysfunction in mood and related disorders
CBD FOR DEPRESSIONAntidepressant-Like and Anxiolytic-Like Effects of Cannabidiol: A Chemical Compound of Cannabis Sativa
CBD FOR DEPRESSIONThe endocannabinoid system and the treatment of mood and anxiety disorders
CBD FOR DEPRESSIONEndocannabinoid signaling in the etiology and treatment of major depressive illness
CBD FOR DEPRESSIONAntidepressant-like effects of cannabidiol in mice: Possible involvement of 5-HT1A receptors
CBD FOR DEPRESSIONPutative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants
CBD FOR DEPRESSIONAntidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa
CBD FOR DEPRESSIONCirculating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
CBD FOR DEPRESSIONSerum contents of endocannabinoids are correlated with blood pressure in depressed women
CBD FOR DEPRESSIONThe therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants
CBD FOR DEPRESSIONAntidepressants and Changes in Concentration of Endocannabinoids and N-Acylethanolamines in Rat Brain Structures
21CBD FOR ENDOCRINE DISORDERSEndocannabinoid system participates in neuroendocrine control of homeostasis
CBD FOR ENDOCRINE DISORDERSThe emerging role of the endocannabinoid system in endocrine regulation and energy balance
CBD FOR ENDOCRINE DISORDERSEndocannabinoids in endocrine and related tumours
CBD FOR ENDOCRINE DISORDERSRole of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas
CBD FOR ENDOCRINE DISORDERSThe role of the endocannabinoid system in the neuroendocrine regulation of energy balance
CBD FOR ENDOCRINE DISORDERSCBD for children with Dravet’s and intractable seizures
CBD FOR ENDOCRINE DISORDERSReport of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy
CBD FOR ENDOCRINE DISORDERSMedicinal marijuana stops seizures, brings hope to a little girl
CBD FOR ENDOCRINE DISORDERSCannabinoids for epilepsy
CBD FOR ENDOCRINE DISORDERSCannabis, cannabidiol, and epilepsy – From receptors to clinical response
CBD FOR ENDOCRINE DISORDERSThe non-psychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability
CBD FOR ENDOCRINE DISORDERSChronic administration of cannabidiol to healthy volunteers and epileptic patients
CBD FOR ENDOCRINE DISORDERSEndocannabinoid system protects against cryptogenic seizures
CBD FOR ENDOCRINE DISORDERSSeizing an opportunity for the endocannabinoid system
CBD FOR ENDOCRINE DISORDERSCannabidiol: promise and pitfalls
CBD FOR ENDOCRINE DISORDERSCannabidivarin (CBDV) suppressespentylenetetrazole (PTZ)-inducedincreases in epilepsy-related gene expression
CBD FOR ENDOCRINE DISORDERSCannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
CBD FOR ENDOCRINE DISORDERSCannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
CBD FOR ENDOCRINE DISORDERSHypnotic and antiepileptic effects of cannabidiol
CBD FOR ENDOCRINE DISORDERSThe cannabinoids as potential antiepileptics
CBD FOR ENDOCRINE DISORDERSCannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats
5CBD FOR FIBROMYALGIAClinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
CBD FOR FIBROMYALGIACannabis use in patients with fibromyalgia: effect on symptoms relief and health-related quality of life
CBD FOR FIBROMYALGIAAssociation of herbal cannabis use with negative psychosocial parameters in patients with fibromyalgia
CBD FOR FIBROMYALGIACannabinoids for fibromyalgia
CBD FOR FIBROMYALGIAMedical Cannabis for the Treatment of Fibromyalgia
4CBD FOR GLAUCOMANeuroprotective effect of (-)Delta9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite
CBD FOR GLAUCOMACannabinoids and glaucoma
CBD FOR GLAUCOMAThe treatment of glaucoma using a non-psychoactive preparation of Cannabis sativa
CBD FOR GLAUCOMACannabinoids for treatment of glaucoma
7CBD FOR HEART DISEASEIs the cardiovascular system a therapeutic target for cannabidiol?
CBD FOR HEART DISEASEAcute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion
CBD FOR HEART DISEASECannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
CBD FOR HEART DISEASEThe Effect of Cannabidiol on Ischemia/Reperfusion-Induced Ventricular Arrhythmias: The Role of Adenosine A1 Receptors
CBD FOR HEART DISEASECannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury
CBD FOR HEART DISEASEEndocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
CBD FOR HEART DISEASEOleamide: A fatty acid amide signaling molecule in the cardiovascular system?
6CBD FOR HUNTINGTONS DISEASENeuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington’s disease
CBD FOR HUNTINGTONS DISEASECannabinoids: Novel medicines for the treatment of Huntington’s disease
CBD FOR HUNTINGTONS DISEASESativex-like combination of phytocannabinoids is neuroprotective in malonate-lesioned rats, an inflammatory model of Huntington’s disease: role of CB(1) and CB(2) receptors
CBD FOR HUNTINGTONS DISEASEControlled clinical trial of cannabidiol in Huntington’s disease
CBD FOR HUNTINGTONS DISEASEProspects for cannabinoid therapies in basal ganglia disorders
CBD FOR HUNTINGTONS DISEASENeuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice
13CBD FOR INFLAMMATIONCannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
CBD FOR INFLAMMATIONThe endocannabinoid system: an emerging key player in inflammation
CBD FOR INFLAMMATIONAnti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice
CBD FOR INFLAMMATIONCannabinoids, endocannabinoids, and related analogs in inflammation
CBD FOR INFLAMMATIONCannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor
CBD FOR INFLAMMATIONCannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
CBD FOR INFLAMMATIONCannabidiol reduces intestinal inflammation through the control of neuroimmune axis
CBD FOR INFLAMMATIONDiabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
CBD FOR INFLAMMATIONCannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement
CBD FOR INFLAMMATIONCannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption
CBD FOR INFLAMMATIONVanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation
CBD FOR INFLAMMATIONCannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death
CBD FOR INFLAMMATIONCannabinoids in clinical practice
9CBD FOR IRRITABLE BOWEL SYNDROMECannabidiol in inflammatory bowel diseases: A brief overview
CBD FOR IRRITABLE BOWEL SYNDROMECannabidiol reduces intestinal inflammation through the control of neuroimmune axis
CBD FOR IRRITABLE BOWEL SYNDROMEClinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
CBD FOR IRRITABLE BOWEL SYNDROMECannabinoid actions at TRPV channels: Effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation
CBD FOR IRRITABLE BOWEL SYNDROMETherapeutic potential of cannabinoid-based drugs
CBD FOR IRRITABLE BOWEL SYNDROMEBeneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease (Biochemical Pharmacology)
CBD FOR IRRITABLE BOWEL SYNDROMECannabinoids and the gut: New developments and emerging concepts
CBD FOR IRRITABLE BOWEL SYNDROMEEndocannabinoids and the gastrointestinal tract
CBD FOR IRRITABLE BOWEL SYNDROMECannabinoids and gastrointestinal motility: Animal and human studies
4CBD FOR KIDNEY DISEASECannabidiol attenuates cisplatin-induced nephrotoxicity by decreasing oxidative/nitrosative stress, inflammation, and cell death
CBD FOR KIDNEY DISEASEChronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay
CBD FOR KIDNEY DISEASEIs There a Legitimate Role for the Therapeutic Use of Cannabinoids for Symptom Management in Chronic Kidney Disease?
CBD FOR KIDNEY DISEASEThe emerging role of the endocannabinoid system in the pathogenesis and treatment of kidney diseases
7CBD FOR LIVER DISEASEThe endocannabinoid system and liver diseases
CBD FOR LIVER DISEASECannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death
CBD FOR LIVER DISEASECannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis
CBD FOR LIVER DISEASETherapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats
CBD FOR LIVER DISEASERole of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol
CBD FOR LIVER DISEASECannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice
CBD FOR LIVER DISEASECannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation
5CBD FOR METABOLIC SYNDROMEThe impact of marijuana use on glucose, insulin, and insulin resistance among US adults
CBD FOR METABOLIC SYNDROMEThe potential use of cannabidiol in the therapy of metabolic syndrome
CBD FOR METABOLIC SYNDROMECannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
CBD FOR METABOLIC SYNDROMEMetabolic syndrome in people with a psychotic illness: is cannabis protective?
CBD FOR METABOLIC SYNDROMECannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome
5CBD FOR MIGRAINESClinical endocannabinoid deficiency (CECD): Can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
CBD FOR MIGRAINESEffects of anandamide in migraine: data from an animal model
CBD FOR MIGRAINESCannabinoids and hallucinogens for headache
CBD FOR MIGRAINESThe endocannabinoid system and migraine
CBD FOR MIGRAINESVariations in the cannabinoid receptor 1 gene predispose to migraine
6CBD FOR MOOD DISORDERSMultiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders
CBD FOR MOOD DISORDERSThe endocannabinoid system and the treatment of mood and anxiety disorders
CBD FOR MOOD DISORDERSThe endocannabinoid system and psychiatric disorders
CBD FOR MOOD DISORDERSThe endocannabinoid system in the regulation of emotions throughout lifespan: A discussion on therapeutic perspectives
CBD FOR MOOD DISORDERSEndocannabinoid system dysfunction in mood and related disorders
CBD FOR MOOD DISORDERSEffects of cannabidiol (CBD) on regional cerebral blood flow
3CBD FOR MOTION SICKNESSMotion sickness, stress and the endocannabinoid system
CBD FOR MOTION SICKNESSDexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system
CBD FOR MOTION SICKNESSThe Effects of Cannabidiol and Tetrahydrocannabinol on Motion‐Induced Emesis
10CBD FOR MULTIPLE SCLEROSISSativex for the management of multiple sclerosis symptoms
CBD FOR MULTIPLE SCLEROSISTHC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis
CBD FOR MULTIPLE SCLEROSISClinical efficacy and effectiveness of Sativex, a combined cannabinoid medicine, in multiple sclerosis-related spasticity
CBD FOR MULTIPLE SCLEROSISCannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors
CBD FOR MULTIPLE SCLEROSISOromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: An uncontrolled, open-label, 2-year extension trial
CBD FOR MULTIPLE SCLEROSISNabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis
CBD FOR MULTIPLE SCLEROSISSativex long-term use: An open-label trial in patients with spasticity due to multiple sclerosis
CBD FOR MULTIPLE SCLEROSISA double-blind, randomized, placebo-controlled, parallel-group study of Sativex, in subjects with symptoms of spasticity due to multiple sclerosis
CBD FOR MULTIPLE SCLEROSISMeta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain(
CBD FOR MULTIPLE SCLEROSISSativex: Clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain
6CBD FOR NAUSEACannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus
CBD FOR NAUSEACannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation
CBD FOR NAUSEAInteraction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews
CBD FOR NAUSEARegulation of nausea and vomiting by cannabinoids
CBD FOR NAUSEACannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats
CBD FOR NAUSEAPreliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting
5CBD FOR NEURODEGENERATIONCannabidiol: A promising drug for neurodegenerative disorders?
CBD FOR NEURODEGENERATIONCannabidiol for neurodegenerative disorders: Important new clinical applications for this phytocannabinoid?
CBD FOR NEURODEGENERATIONTransdermal delivery of cannabidiol attenuates binge alcohol-induced neurodegeneration in a rodent model of an alcohol use disorder
CBD FOR NEURODEGENERATIONMemory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders
CBD FOR NEURODEGENERATIONCannabidiol normalizes caspase 3, synaptophysin, and mitochondrial fission protein DNM1L expression levels in rats with brain iron overload: implications for neuroprotection
18CBD FOR NEUROPATHIC PAINMeta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
CBD FOR NEUROPATHIC PAINSativex: Clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain
CBD FOR NEUROPATHIC PAINCannabis, pain, and sleep: Lessons from therapeutic clinical trials of Sativex, a cannabis-based medicine
CBD FOR NEUROPATHIC PAINSativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial
CBD FOR NEUROPATHIC PAINCannabinoids for neuropathic pain
CBD FOR NEUROPATHIC PAINNeuropathic orofacial pain: Cannabinoids as a therapeutic avenue
CBD FOR NEUROPATHIC PAINOromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial
CBD FOR NEUROPATHIC PAINThe non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain
CBD FOR NEUROPATHIC PAINVanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation
CBD FOR NEUROPATHIC PAINCannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT1A receptors without diminishing nervous system function or chemotherapy efficacy
CBD FOR NEUROPATHIC PAINAntihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: Mechanisms involved
CBD FOR NEUROPATHIC PAINNon-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action
CBD FOR NEUROPATHIC PAINCannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
CBD FOR NEUROPATHIC PAINRole of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes
CBD FOR NEUROPATHIC PAINCannabinoids in the management of difficult to treat pain
CBD FOR NEUROPATHIC PAINMulticenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain
CBD FOR NEUROPATHIC PAINMarijuana extract helps prevent chemo pain
CBD FOR NEUROPATHIC PAINPot users less likely to take painkillers
6CBD FOR OBESITYThe impact of marijuana use on glucose, insulin, and insulin resistance among US adults
CBD FOR OBESITYCannabinol and cannabidiol exert opposing effects on rat feeding patterns
CBD FOR OBESITYCannabis and Δ9-tetrahydrocannabinol (THC) for weight loss?
CBD FOR OBESITYThe endocannabinoid system in obesity and type 2 diabetes
CBD FOR OBESITYRole of the endocannabinoid system in abdominal obesity and the implications for cardiovascular risk
CBD FOR OBESITYCannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
3CBD FOR OCDPlasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour (PubMed)
CBD FOR OCDPlasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive–compulsive behaviour
CBD FOR OCDInvolvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice
7CBD FOR PARKINSONS DISEASEEffects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial
CBD FOR PARKINSONS DISEASEProspects for cannabinoid therapies in basal ganglia disorders
CBD FOR PARKINSONS DISEASEEvaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson’s disease: Importance of antioxidant and cannabinoid receptor-independent properties
CBD FOR PARKINSONS DISEASECannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson’s disease
CBD FOR PARKINSONS DISEASECannabidiol for the treatment of psychosis in Parkinson’s disease
CBD FOR PARKINSONS DISEASESymptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of Parkinson’s disease
CBD FOR PARKINSONS DISEASETherapeutic potential of cannabinoids in CNS disease
3CBD FOR PRIONNonpsychoactive cannabidiol prevents prion accumulation and protects neurons against prion toxicity
CBD FOR PRIONCannabidiol: A prion therapy for mice?
CBD FOR PRIONAlteration of the endocannabinoid system in mouse brain during prion disease
13CBD FOR PTSDThe endocannabinoid system provides an avenue for evidence-based treatment development for PTSD
CBD FOR PTSDReductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the world trade center attacks
CBD FOR PTSDEnhancing cannabinoid neurotransmission augments the extinction of conditioned fear
CBD FOR PTSDCannabidiol blocks long-lasting behavioral consequences of predator threat stress: Possible involvement of 5HT1A receptors
CBD FOR PTSDStress switches cannabinoid type-1 (CB1) receptor-dependent plasticity from LTD to LTP in the bed nucleus of the stria terminalis
CBD FOR PTSDMitigation of post-traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence
CBD FOR PTSDCannabinoid modulation of fear extinction brain circuits: A novel target to advance anxiety treatment
CBD FOR PTSDThe endocannabinoid system and extinction learning
CBD FOR PTSDA current overview of cannabinoids and glucocorticoids in facilitating extinction of aversive memories: potential extinction enhancers
CBD FOR PTSDCannabinoids and traumatic stress modulation of contextual fear extinction and GR expression in the amygdala-hippocampal-prefrontal circuit
CBD FOR PTSDNon-antidepressant long-term treatment in post-traumatic stress disorder
CBD FOR PTSDThe anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: Involvement of the endocannabinoid system
CBD FOR PTSDModulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors
4CBD FOR RHEUMATISMCannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
CBD FOR RHEUMATISMEfficacy, tolerability and safety of cannabinoids in chronic pain associated with rheumatic diseases
CBD FOR RHEUMATISMClinical Implications for Cannabinoid Use in the Rheumatic Diseases
CBD FOR RHEUMATISMCannabinoids in the Management of Musculoskeletal or Rheumatic Diseases
12CBD FOR SCHIZOPHRENIACannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
CBD FOR SCHIZOPHRENIACannabidiol as a potential treatment for psychosis
CBD FOR SCHIZOPHRENIACannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
CBD FOR SCHIZOPHRENIAMedical use of cannabis. Cannabidiol: A new light for schizophrenia?
CBD FOR SCHIZOPHRENIAA critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation
CBD FOR SCHIZOPHRENIAPeripheral endocannabinoid system dysregulation in first-episode psychosis
CBD FOR SCHIZOPHRENIACannabinoids and schizophrenia: Therapeutic prospects
CBD FOR SCHIZOPHRENIAAntipsychotic-like effects of cannabidiol and rimonabant: Systematic review of animal and human studies
CBD FOR SCHIZOPHRENIACannabidiol monotherapy for treatment-resistant schizophrenia
CBD FOR SCHIZOPHRENIACannabis with high cannabidiol content is associated with fewer psychotic experiences
CBD FOR SCHIZOPHRENIAMarijuana compound treats schizophrenia with few side effects: Clinical trial
CBD FOR SCHIZOPHRENIAClearing the smoke: what do we know about adolescent cannabis use and schizophrenia?
3CBD FOR SICKLE CELL ANEMIAPain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: Modulation by cannabinoids
CBD FOR SICKLE CELL ANEMIACannabis use in sickle cell disease: A questionnaire study
CBD FOR SICKLE CELL ANEMIACannabinoid Receptor-Specific Mechanisms To Alleviate Pain In Sickle Cell Anemia Via Inhibition Of Mast Cell Activation And Neurogenic Inflammation
8CBD FOR SKIN CONDITIONSCannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis
CBD FOR SKIN CONDITIONSCannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes
CBD FOR SKIN CONDITIONSThe endocannabinoid system of the skin in health and disease: Novel perspectives and therapeutic opportunities
CBD FOR SKIN CONDITIONSEpigenetic control of skin differentiation genes by phytocannabinoids
CBD FOR SKIN CONDITIONSEndocannabinoids modulate human epidermal keratinocyte proliferation and survival via the sequential engagement of cannabinoid receptor-1 and transient receptor potential vanilloid-1
CBD FOR SKIN CONDITIONSCannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation
CBD FOR SKIN CONDITIONSAttenuation of allergic contact dermatitis through the endocannabinoid system
CBD FOR SKIN CONDITIONSTopical cannabinoid agonists. An effective new possibility for treating chronic pruritus
7CBD FOR SLEEP DISORDERSThe nonpsychoactive Cannabis constituent cannabidiol is a wake-inducing agent
CBD FOR SLEEP DISORDERSCannabis, pain, and sleep: Lessons from therapeutic clinical trials of Sativex, a cannabis-based medicine
CBD FOR SLEEP DISORDERSEffects of acute systemic administration of cannabidiol on sleep-wake cycle in rats
CBD FOR SLEEP DISORDERSEffect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults
CBD FOR SLEEP DISORDERSCannabidiol, a constituent of Cannabis sativa, modulates sleep in rats
CBD FOR SLEEP DISORDERSEndocannabinoid modulation of cortical up-states and NREM sleep
CBD FOR SLEEP DISORDERSIntranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in Sprague-Dawley rat
4CBD FOR SPINAL CORD INJURYCannabidiol-treated rats exhibited higher motor score after cryogenic spinal cord injury
CBD FOR SPINAL CORD INJURYCannabis effect on spasticity in spinal cord injury
CBD FOR SPINAL CORD INJURYAn Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain From Spinal Cord Injury and Disease
CBD FOR SPINAL CORD INJURYModulation of Inflammatory Responses by a Cannabinoid-2–Selective Agonist after Spinal Cord Injury
13CBD FOR STRESSEndogenous cannabinoid signaling is essential for stress adaptation
CBD FOR STRESSRegulation of endocannabinoid signaling by stress: Implications for stress-related affective disorders
CBD FOR STRESSFunctional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output
CBD FOR STRESSNeuromodulators, stress and plasticity: a role for endocannabinoid signalling
CBD FOR STRESSDownregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress
CBD FOR STRESSEndocannabinoids and stress
CBD FOR STRESSStress regulates endocannabinoid-CB1 receptor signaling
CBD FOR STRESSChronic Stress Impairs α1-Adrenoceptor-Induced Endocannabinoid-Dependent Synaptic Plasticity in the Dorsal Raphe Nucleus
CBD FOR STRESSEndocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance
CBD FOR STRESSCannabinoid receptor activation prevents the effects of chronic mild stress on emotional learning and LTP in a rat model of depression
CBD FOR STRESSCannabinoids ameliorate impairments induced by chronic stress to synaptic plasticity and short-term memory
CBD FOR STRESSThe anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
CBD FOR STRESSLow-frequency stimulation evokes serotonin release in the nucleus accumbens and induces long-term depression via production of endocannabinoid
6CBD FOR STROKE/TBICannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury
CBD FOR STROKE/TBICannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism
CBD FOR STROKE/TBICannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism (
CBD FOR STROKE/TBICannabidiol administration after hypoxia-ischemia to newborn rats reduces long-term brain injury and restores neurobehavioral function
CBD FOR STROKE/TBIProtective Effects of Cannabidiol Against Hippocampal Cell Death and Cognitive Impairment Induced by Bilateral Common Carotid Artery Occlusion in Mice
CBD FOR STROKE/TBIRepeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance

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